There are two different things here: the style of the iframe block and the style of the page embedded in the iframe. You can set the style of the iframe block the usual way:
<iframe name="iframe1" id="iframe1" src="empty.htm"
frameborder="0" border="0" cellspacing="0"
style="border-style: none;width: 100%; height: 120px;"></iframe>
The style of the page embedded in the iframe must be either set by including it in the child page:
<link type="text/css" rel="Stylesheet" href="Style/simple.css" />
Or it can be loaded from the parent page with Javascript:
var cssLink = document.createElement("link");
cssLink.href = "style.css";
cssLink.rel = "stylesheet";
cssLink.type = "text/css";
frames['iframe1'].document.head.appendChild(cssLink);