Combine CSS Grid and Flexbox for responsive layouts effectively.

This question explores the synergy between CSS Grid and Flexbox, two powerful layout mechanisms in CSS. It delves into their individual strengths — CSS Grid for two-dimensional layouts and Flexbox for one-dimensional layouts — and encourages candidates to demonstrate how they can leverage both techniques together to achieve complex responsive designs. Candidates are expected to showcase their understanding of when and why combining these methods is advantageous, along with practical examples illustrating their implementation strategies. The question also invites discussion on best practices for maintaining clean, maintainable code while harnessing the full potential of CSS Grid and Flexbox in modern web development.